How the ROPA method is evaluated based on success probabilities

The ROPA method (Reception of Oocytes from Partner) is an assisted reproduction technique within in vitro fertilization (IVF) that allows one woman to provide the eggs while the other carries the pregnancy.

Before starting treatment, a complete medical evaluation is necessary to estimate success rates and design a personalized plan.

Step 1: Evaluation of both women

Evaluation of the egg donor partner

The following are assessed:

• Ovarian reserve, through:

  • Anti-Müllerian hormone

  • Antral follicle count

  • FSH and estradiol

• Age, which directly affects:

  • Number of eggs retrieved

  • Egg quality

  • Embryo viability

Better ovarian reserve equals higher success rates.

Evaluation of the gestational partner

For the woman who will carry the pregnancy:

• Vaginal ultrasound

• Endometrial thickness and receptivity

• Gynecological history

• Hysteroscopy if needed to rule out uterine abnormalities

A healthy uterus significantly improves implantation chances.

How embryos are created in ROPA

1. Ovarian stimulation of the donor

2. Egg retrieval

3. Fertilization with donor sperm

4. Embryo culture to day 5

5. Embryo transfer to the gestational partner

Embryo quality is one of the most important predictors of success.

What determines ROPA success rates?

Key factors include:

• Donor’s age

• Embryo quality

• Uterine environment of the gestational partner

• Laboratory quality and expertise

• Medical history of both women

Advantages of the ROPA method

• Both partners actively participate

• Shared biological motherhood

• Similar success rates to conventional IVF

• Ability to select the best embryo before transfer

The ROPA method is a meaningful and effective option for female couples.

With proper evaluation, personalized treatment, and a specialized fertility team, success rates are highly favorable.